In Vitro Antibacterial Activity of Genisteinand Quercetin against Escherichia Coli Isolated from Clinical Samples
نویسندگان
چکیده
Objective: The aim of this study was to investigate the antibacterial activity of Genistein and Quercetin against pathogens of the urinary tract infection (UTI). Methods: An in vitro study was carried out using the following bacterial strains involved in UTI diseases using well diffusion (WD) testing: Escherichia coli (ATCC 25922) and 10 strains were compiled from Aleppo Hospital. It was from women and men have UTI. The antibacterial activity of Genistein and Quercetin was determined in the form of inhibition zone using agar WD testing. Results: In all experiments, results obtained indicated that Genistein and Quercetin had inhibitory effects on E. coli (ATCC 25922) and some 10 strains. This study showed that Genistein and Quercetin were active against the tested bacterial strains. Conclusion: The Genistein showed better antibacterial effect the tested bacterial strains. Therefore, the Genistein and Quercetin could be encouraged for further development in caries prevention and treatment.
منابع مشابه
Antibacterial Activity of the Peptide Microcin J25 Produced by Escherichia coli
Background and objectives: Bacteriocins are generally active antimicrobial peptides effective against bacteria closely related to the producer. Escherichia coli produce two bacteriocins: colicins and microcins. Microcin J25 (Mcc J25) is an antibacterial peptide that inhibits bacterial transcription by disrupting the nucleotide-uptake channel of bacterial RNA polymerase. The objective of this st...
متن کاملIn vitro evaluation of antibacterial activity of verbascoside, lemon verbena extract and caffeine in combination with gentamicin against drug-resistant Staphylococcus aureus and Escherichia coli clinical isolates
Objective: In recent years, there has been an increasing interest in using herbal products to overcome bacterial resistance. The aim of this study was to investigate the effect of lemon verbena aqueous extract, verbascoside and caffeine in combination with gentamicin against standard and clinical isolates of Staphylococcus aureus and Escherichia coli strains. Materials and Methods: The MIC and ...
متن کاملIn Vitro Antibacterial Activity of Rheum ribes Extract Obtained from Various Plant Parts Against Clinical Isolates of Gram-Negative Pathogens
Rheum ribes is among the Polygonaceae family which is endemic in Iran and a few neighboring countries. In this investigation, antibacterial effects of root, stalk and leaves extracts of Rheum ribes on a few common clinical isolates of gram negative pathogens were studied, using the cup plate and paper disc methods. Gram negative microorganisms studied were Escherichia coli, Klebsiella pneumonia...
متن کاملIn Vitro Antibacterial Activity of Rheum ribes Extract Obtained from Various Plant Parts Against Clinical Isolates of Gram-Negative Pathogens
Rheum ribes is among the Polygonaceae family which is endemic in Iran and a few neighboring countries. In this investigation, antibacterial effects of root, stalk and leaves extracts of Rheum ribes on a few common clinical isolates of gram negative pathogens were studied, using the cup plate and paper disc methods. Gram negative microorganisms studied were Escherichia coli, Klebsiella pneumonia...
متن کاملEvaluation of antibacterial effect of silver nanoparticles against Escherichia coli isolates producing broad-spectrum beta-lactamases isolated from urinary tract infections
Introduction Considering the growth of antibiotic resistance and the study of new ways in Nanobiotechnology, this study examines the therapeutic effect of silver nanoparticles on E.coli bacteria to control and find new treatments against ESBL isolates of Escherichia coli. Materials and Methods For 100 samples of Escherichia coli, antibiotic resistance was determined by disc method for 3rd gen...
متن کامل